Welcome to the Pentracor GmbH

Pentracor is a medical device company that has developed a breakthrough innovation for the treatment of acute myocardial infarction. Our first product on the German market is PentraSorb® CRP and has attracted much attention since the completion of a landmark clinical trial. Pentracor has a research and development pipeline in several therapeutic areas based on our unique expertise in immunology.

C-reactive protein (CRP) is an antibody of prehistoric immune systems and the innate immune system. It binds to proteins of the complement system forming immunocomplexes. In heart attack and stroke CRP increases primary damage. Further, the severity of rheumatic diseases is often determined by the amount of CRP.

The CRP adsorber (PentraSorb® CRP) is CE-marked. The corresponding Quality management system certificate according to EN ISO 13485 and the EC Certificate of Conformity in accordance with Directive 93/42/EEC are available.

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PentraSorb® CRP

Since November 2014 Pentracor GmbH is responsible and certified for the production and distribution of CRP adsorbers according to EN ISO 13485. The PentraSorb® CRP is an adsorber for the selective depletion of C-reactive protein (CRP).

CRP Adsorber

In the case of organ damage (e.g. heart attack or stroke), CRP marks cells capable of regeneration, which are then eliminated by the immune system. This increases the primary damage.

With the help of the PentraSorb® CRP can be removed from the blood with the aim of reducing this damage.

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CRP apheresis

In CRP apheresis, CRP is selectively removed from the patient's blood plasma.

The application of PentraSorb® CRP is comparable to dialysis and can be performed in an outpatient or inpatient setting.

During the treatment, blood plasma is passed through the PentraSorb® CRP, which then selectively removes CRP from it.

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Application

In principle, CRP reduction can induce therapeutic benefits in a number of acute and chronic diseases.

PentraSorb® CRP is a potential therapeutic option for diseases where elevated CRP levels are associated with a poor prognosis.

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Dates

June 5.-7.: "Herztage" of the German Cardiac Society in Bonn

News

Obituary: Rudolf Kunze

22.05.2023

On monday, May 22nd 2023 our great friend mentor and provider of ideas Dr. Rudolf Kunze passed away, peacefully. He leaves a great void. We miss him.

Update on the clinical relevance of the C-reactive protein in Forum Sanitas 

25.04.2023

An update on the clinical relevance of the C-reactive protein was published in the second edition of 2023 in the medical magazine Forum Sanitas. Dr. Wolfgang Ries and Dr. Fabrizio Esposito report from the practice of therapies for acute, necrotic pancreatitis and severe myocardial infarction.

Positive assessment of the potential of CRP apheresis by the G-BA 

16.05.2023

Zum Klären der Effizienz der CRP-Apherese-Therapie hat sich die Pentracor GmbH bereits im November 2022 an den G-BA (Gemeinsamer Bundesausschuss, das oberste Beschlussgremium der gemeinsamen Selbstverwaltung im deutschen Gesundheitswesen) gewendet.

Pentracor at the annual convention of the German Cardiac Society

19.04.2023

We have been at the 89th annual convention of the German Cardiac Society in Mannheim where we had great conversations with new and old contacts in the cardiologists community.

New comment on CRP apheresis

22.03.2023

An article entitled “C-reactive Protein Apheresis in Acute Myocardial Infarction” was published in the journal Current Pharmaceutical Design, April 2023 issue, and addresses the topic of C-reactive protein apheresis (CRP-A) therapy in patients with acute myocardial infarction.

FDA grants designation as Breakthrough Device

28.11.2022

The FDA has granted PentraSorb CRP designation as a Breakthrough Device. A remarkable achievement.