Pentracor is a medical device company that has developed a breakthrough innovation for the treatment of acute myocardial infarction. Our first product on the German market is PentraSorb® CRP and has attracted much attention since the completion of a landmark clinical trial. Pentracor has a research and development pipeline in several therapeutic areas based on our unique expertise in immunology.
C-reactive protein (CRP) is an antibody of prehistoric immune systems and the innate immune system. It binds to proteins of the complement system forming immunocomplexes. In heart attack and stroke CRP increases primary damage. Further, the severity of rheumatic diseases is often determined by the amount of CRP.
The CRP adsorber (PentraSorb® CRP) is CE-marked. The corresponding Quality management system certificate according to EN ISO 13485 and the EC Certificate of Conformity in accordance with Directive 93/42/EEC are available.
Since November 2014 Pentracor GmbH is responsible and certified for the production and distribution of CRP adsorbers according to EN ISO 13485. The PentraSorb® CRP is an adsorber for the selective depletion of C-reactive protein (CRP).
New publication: Being Eaten Alive
16.08.2023
In tissues with insufficient oxygen supply, CRP initiates the disposal of vital cells. They are being eaten alive. This leads to damage, e.g. after heart attack. Therefore, CRP is obviously a therapeutic target molecule.
New publication about CRP as a target for therapy to reduce inflammation
26.07.2023
Frontiers in Immunology published an article by three Canadian authors on CRP as a therapeutic target.
New publication on CRP apheresis as a therapeutic option in STEMI
11.07.2023
The cardiac MRI tissue characteristics of myocardial damage correlate with the extent of left ventricular dysfunction in the acute phase of severe myocardial infarction (STEMI). Since lowering CRP levels leads to smaller infarcts and better heart function, it could be considered as an additional therapeutic option in STEMI.
Call for studies by the DCCV on CRP apheresis in Crohn's disease and ulcerative colitis
28.6.2023
The German Crohn's Disease / Ulcerative Colitis Association and the Federal Association for Chronic Inflammatory Diseases of the Digestive Tract (DCCV) e.V. are looking for study participants for the clinical study on the selective depletion of the C-reactive protein by means of therapeutic apheresis (CRP apheresis) in Crohn's disease and ulcerative colitis ( CAMCRO1).
Obituary: Rudolf Kunze
22.05.2023
On monday, May 22nd 2023 our great friend mentor and provider of ideas Dr. Rudolf Kunze passed away, peacefully. He leaves a great void. We miss him.
Update on the clinical relevance of the C-reactive protein in Forum Sanitas
25.04.2023
An update on the clinical relevance of the C-reactive protein was published in the second edition of 2023 in the medical magazine Forum Sanitas. Dr. Wolfgang Ries and Dr. Fabrizio Esposito report from the practice of therapies for acute, necrotic pancreatitis and severe myocardial infarction.
