"C-reactive protein triggers cell death in ischemic cells":

In the Research Topic "Diagnostic and Therapeutic Applications of Pentraxin and Pentraxin-Associated Proteins" of the journal Frontiers in Immunology, a review on the pathomechanism of CRP in organ-damaging inflammation was published.

This article clearly summarizes how CRP labels and eliminates damaged and ischemic cells during inflammation after e.g. myocardial infarction or stroke and thereby fundamentally contributes to the overall organ damage.